To do so, the church retained the expertise of noted architect Robert Willison, who is credited with designing at least a dozen significant buildings throughout Colorado, and Italian-born stonemason Nunzio Grasso, a pivotal figure in the nascent Grand Junction Italian-American community.

With its rock-faced stone walls, square bell tower, and semicircular masonry arches, the Sacred Heart Church is an excellent example of the Romanesque Revival style applied to a house of worship and a fine example of the design expertise and craftsmanship of Willison and Grasso. The church's original artistic stained-glass windows further complement the building’s fine design and stonework.