In October of 1904, the Cabrini Sisters established an orphanage at the Notary Home in North Denver. In 1905, Cabrini’s order moved the orphanage into a renovated farmhouse at 48th and Federal in Denver. The original Regina Coeli, or “Queen of Heaven” building was replaced in 1921 by the new facility seen in this image. The orphanage remained in operation until 1967.